燕达国际医院消化科 郑日男 内镜在消化系疾病诊治中的应用 内镜发展史 1806-硬式内镜 ---德国法兰克福,Bozzin 1957-纤维内镜 ---美国医生,Hirschowitz 1983-电子胃镜 ---美国,Welch Allyn公司 ---电视监视器 Chromoendoscopy Magnifying endoscopy IPCL NBI, AFI EMR ESD ERCP EUS NOTES Esophageal anatomy Ce: cervical esophaguse Ut: upper thoracic esophagus Mt: middle thoracic esophagus Lt: lower thoracic esophagus Ae:Abdominal esophagus Epithelium Lamina prop. Mascularis mucosae Submucosa Prop. muscle Serosa m1 m2 m3 sm1 sm2 sm3 Depth of tumor invasion 正常食管组织病理 Epithelium Lamina propria Muscularis mucosae Circular muscle Longitudinal muscle Submucosa Serosa Epidemiology of the esophageal cancer Carcinoma of the esophagus incidence North china 130/100,000 population America 5/100,000 population Japan 5/100,000 population Urban China Rural China United States United Kingdom Switzerland
(2001) 0 5 10 15 20 25 30 35 40 45 50 55
(2000)
(1999)
(1999)
(1999)
(1999)
(1998)
(1999)
(1999)
(1999)
(1999)
(1999)
(2000)
(1997)
(1999) Mortality per 100,000 males Japan Korea Italy Canada Germany France Sweden Australia Russia Argentina Country Hatakeyama et al. nature acer 2004 Sep;4(9):688-94 食管癌的病理 (病変部位) 日本 Mt: % Lt: % Ut: % 中国 Mt:-% Lt:-% Ut:-%