5血液淋巴和血发生.ppt

组织胚胎学课件 七年制英文医学班专用
中国医科大学
基础医学院
组胚—英文教学组
Chapter 5 Blood and Hemopoiesis
1.       Components:
---formed elements: 45%
red blood cell-erythrocyte
white blood cell-leukocyte
platelets
---plasma: 55%, PH -, 90% water
contain: plasma protein(albumin, globulin, fibrinogen), lipidprotein, enzymes, hormone, vitamin, anic salt and products of metabolism
*serum: is plasma in which the fibrinogen has been removed by clotting
Blood smear: Wright or Giemsa stain methods
1.   Cells
1) erythrocyte, red blood cell
---normal number:
(-)X1012/L in male
(-)X1012/L in female
---structure:
biconcave discs in shape,
- um in diameter, 1-2um thick
no nucleus anella
filled with hemoglobin, Hb: about 1/3
-normal number: 120-150g/L in male
105-135g/L in female
-combine and transfer O2 and CO2
erythrocyte membrane skeleton:
-change shape
-ponent is spectrin and actin
blood type antigen: A, B :
-membrane protein
-ABO blood type
-hemolysis→erythrocyte ghost
*anemia: RBC < /L or Hb <100g/L
* reticulocyte:
-1% of total erythrocyte
population or 3-6% in naonate
immature cell
remained ribosome-work structure when stained with brilliant cresyl blue
will disappear after 1-3 days
---life span: 120 days
2) leukocyte
---a group of large cells with nucleus
---involve in defense and immune reaction
---normal number: (-10) X109/L
---classification:
granulocytes: /neutrophil
/eosinophil
/basophil
agranulocytes:
/lympocyte
/monocyte
①     neutrophil:
---normal percentage:
50-70% of total leukocyte population
---structure:
LM:
round, 10-12um in diameter
rob-liked or poly morphous nucleus, 2-5 lobes
fine neutrophilic granules-pink cytoplasm