该【儿科学教学课件-17传染性单核细胞增多症(上) 】是由【小落意】上传分享,文档一共【24】页,该文档可以免费在线阅读,需要了解更多关于【儿科学教学课件-17传染性单核细胞增多症(上) 】的内容,可以使用淘豆网的站内搜索功能,选择自己适合的文档,以下文字是截取该文章内的部分文字,如需要获得完整电子版,请下载此文档到您的设备,方便您编辑和打印。儿科学教学课件-17传染性单核细胞增多症(上)IntroductionInfectiousmononucleosis(IM)isaninfectiousdiseasecausedbyEpstein-Barrvirus(EBV).Theclinicalfeaturesincludefever,pharyngitis,-Barrvirus(EBV):double-strandedDNAvirus---Family:Herpesviridae---Subfamily:γ--reactiveLymphotropicvirusjustinfectingB-LCcapacitytohaveBlymphocyteproliferateinfinitely(immortalization)Epstein-Barrvirus(EBV)Etiology3、ViralAntigenSystemsviralcapsidantigen,VCAEBnuclearantigen,EBNAearlyantigen,EAlymphocyte-detectedmembraneantigen,LYDMAmembraneantigen,,:Contacttransmissionthroughthemouth(exchangeofsaliva)-LCinpharynxpharyngitisLymphadenopathyincervicalnodesexcreteEBVContinuouslyorintermittentlyB-LCintheperipheralbloodandtheentirelymphoreticularsystemviremiaActivationofpolyclonalB-LCpolyclonalantibodiesSpecificAbsheterophilAbautoantibodyTcresponsedtotheinfectedB-LCEffectonB-LCcontainingEBVatypicalLC↑Hepatosplenomegaly,lymphadenectasis,myocarditis,pneumonia,-LCSpecificAbsPathologyThebasicpathologicalchangeisthebenignlymphadenosisThemaindamageisinmonocyte-macrophagesystemLymphnodes:non-pyogeniclymphadenectasiswithLCandmonocyte-macrophagesystemproliferationSpleen:lotsofatypicalLCanssuchasliver,heart,kidney,S,:5~:80%.sorethroat,tonsillarenlargement,hyperemia,edemaandexudates(50%):80~100%.:hepatomegaly:30~50%.Amongthem,2/:50~70%:10%:stuffnose,snore,edemaoftheeyelids,etc临床表现
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